When you spend hours at your desk every day, even the smallest features of your workspace—such as the position of your monitor or the height of your chair—can greatly affect your productivity and even your health. Here’s what science says about the best way to set up your office for ergonomics and productivity.

Your workspace shouldn’t wear you down every day, but that’s what uncomfortable chairs, messy desks, and poor lighting do—even though you might not notice these things day after day. With a few adjustments, however, you can improve your working environment and keep your desk from killing you.